NIH Grant Awarded for Multiple Sclerosis Research

Professors Jennifer McDonough (PI) and Ernie Freeman (PI) (Department of Biological Sciences) together with Professor Roger Gregory (co-PI) (Department of Chemistry and Biochemistry) have been awarded a two-year, $398,682 grant from the National Institutes of Health to support their project “Neuronal Expression of Hemoglobin in Multiple Sclerosis Cortex.”

Hemoglobin is a protein that transports oxygen in the blood, but surprisingly, it is also expressed by neurons and may be involved in neuronal respiration. Recent work by the research group at ��ֱ�� found that hemoglobin expression is increased in multiple sclerosis brain tissue compared with controls [Broadwater et al, Biochimica et Biophysica Acta, 1812 (2011) 630–641]. The goal of this NIH funded research is to understand the regulation and function of hemoglobin expression in neurons, as well as the distribution and extent of hemoglobin expression in the brain and its significance to the neuropathology of multiple sclerosis.

Dr. Roger Gregory
Hemoglobin expression in multiple sclerosis postmortem brain tissue detected by immunofluorescent staining with antibodies to hemoglobin (red) and neurofilament (green).

POSTED: Saturday, September 29, 2012 04:34 PM

UPDATED: Saturday, December 03, 2022 01:02 AM

From Loss to Legacy

For Adedayo Adeagbo, a Ph.D. candidate in medical sociology at ��ֱ�� State University, working with older adults isn't just a research interest -- it's a promise she made to the grandmother she couldn't save.

She says she can still see the bruises. Even years later, even thousands of miles away from where she grew up in Nigeria, the memory of her grandmother's final days haunts and drives her in equal measure.

Bridging Generations

In an era where social media connections replace face-to-face interactions and political divisions seem insurmountable, one ��ֱ�� State University professor has found an antidote: bringing college students and older adults together through simple, meaningful human connection.

Where the Classroom Meets the Field

By day, Will Kalkhoff, Ph.D., is a professor in ��ֱ�� State's Department of Sociology and Criminology, teaching courses on criminal justice, researching police officer performance and mentoring students on their path to careers in sociology, law enforcement and public safety.

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