NIH Grant Awarded for Multiple Sclerosis Research

Professors Jennifer McDonough (PI) and Ernie Freeman (PI) (Department of Biological Sciences) together with Professor Roger Gregory (co-PI) (Department of Chemistry and Biochemistry) have been awarded a two-year, $398,682 grant from the National Institutes of Health to support their project “Neuronal Expression of Hemoglobin in Multiple Sclerosis Cortex.”

Hemoglobin is a protein that transports oxygen in the blood, but surprisingly, it is also expressed by neurons and may be involved in neuronal respiration. Recent work by the research group at ��ֱ�� found that hemoglobin expression is increased in multiple sclerosis brain tissue compared with controls [Broadwater et al, Biochimica et Biophysica Acta, 1812 (2011) 630–641]. The goal of this NIH funded research is to understand the regulation and function of hemoglobin expression in neurons, as well as the distribution and extent of hemoglobin expression in the brain and its significance to the neuropathology of multiple sclerosis.

Dr. Roger Gregory
Hemoglobin expression in multiple sclerosis postmortem brain tissue detected by immunofluorescent staining with antibodies to hemoglobin (red) and neurofilament (green).

POSTED: Saturday, September 29, 2012 04:34 PM

UPDATED: Saturday, December 03, 2022 01:02 AM

International Student Champions Education, Service and Culture at ��ֱ�� State

When Arslan Kalandarov arrived at ��ֱ�� State University from Turkmenistan, he carried with him more than just luggage. As the first in his family to attend college, he brought a deep sense of responsibility, determination and pride in his cultural heritage.

“I was incredibly happy when I got my first on-campus job,” he said. “After coming to the U.S., I knew I had a responsibility to become independent. When I got the job, I realized I could support myself financially, and I didn’t want to burden my family.”

Twinning and Winning: Brothers Begin First Year as Rising Juniors

The first thing you will learn about brothers Will and Ray Maynard is that they are twins – not identical in looks, but in nearly all other aspects.

Flash Focus: Giovanni Tripi

Meet Giovanni Tripi, a member of the Honors College and a senior biology major with minors in public health and forensic anthropology, from Lyndhurst, Ohio.

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